TRANSGENEIC NON-HUMAN ANIMAL MODEL FOR ACCELERATED AGING AND/OR AGE-RELATED SYMPTOM, AND USE THEREOF

Latest bibliographic data on file with the International Bureau ??? Submit observation
Pub. No.: ?? WO/2013/106662 ?? International Application No.: ?? PCT/US2013/021165 Publication Date: 18.07.2013 International Filing Date: 11.01.2013
IPC:	A01K 67/00 (2006.01), C07H 21/00 (2006.01) A HUMAN NECESSITIES 01 AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING K ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS 67 Rearing or breeding animals, not otherwise provided for; New breeds of animals C CHEMISTRY; METALLURGY 07 ORGANIC CHEMISTRY H SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS 21 Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Applicants:	ADVANCED GENOMIC TECHNOLOGY, LLC [US/US]; 5100 U.S. Highway 42 Louisville, KY 40241 (US)
Inventors:	WANG, Eugenia; (US)
Agent:	STEIN, Michael, D.; WOODCOCK WASHBURN LLP Cira Center, 12th Floor 2929 Arch Street Philadelphia, PA 19104 (US)
Priority Data:	61/586,291 ? 13.01.2012 ? US 61/586,361 ? 13.01.2012 ? US 61/636,477 ? 20.04.2012 ? US
Title	(EN) TRANSGENEIC NON-HUMAN ANIMAL MODEL FOR ACCELERATED AGING AND/OR AGE-RELATED SYMPTOM, AND USE THEREOF (FR) MOD?LE D'ANIMAL TRANSG?NIQUE NON HUMAIN POUR LE VIEILLISSEMENT ACC?L?R? ET/OU UN SYMPT?ME LI? ? L'?GE, ET SON UTILISATION
Abstract:	(EN)A transgenic, non-human animal model for accelerated aging and/or age- related symptom, recombinant nucleic acid molecules, cells and methods that can be used to make such animal model and cells, methods of using the animal model and cells, to descendants of the transgenic non-human animal, obtained by breeding with the same or with another phenotype, and to a cell line or primary cell culture or to an organotypic brain slice culture, derived from the transgenic non-human animal or its descendants are disclosed. (FR)L'invention concerne un mod?le d'animal transg?nique non humain pour le vieillissement acc?l?r? et/ou un sympt?me li? ? l'?ge, des mol?cules d'acide nucl?ique recombin?, des cellules et des proc?d?s qui peuvent ?tre utilis?s pour produire ce mod?le animal et ces cellules, des proc?d?s d'utilisation du mod?le animal et des cellules, des descendants de l'animal non humain transg?nique, obtenus par croisement avec le m?me ph?notype ou un autre, et une lign?e cellulaire ou une culture de cellules primaire ou une culture de tranche de cerveau organotypique, d?riv?e de l'animal non humain transg?nique ou de ses descendants.
Designated States:	AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, RU, TJ, TM) European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Publication Language:	English (EN)
Filing Language:	English (EN)

Source: http://patentscope.wipo.int/search/en/detail.jsf?docId=WO2013106662&recNum=1&docAn=US2013021165&queryString=sirt&maxRec=378

cubs cj wilson ellsbury brad pitt and angelina jolie brad and angelina herniated disc luke scott