Thursday, February 21, 2013

UC San Diego Cancer Scientist Wins $3 Million Award

Napoleone Ferrara one of 11 winners of inaugural Breakthrough Prize

Napoleone Ferrara, MD, PhD

Napoleone Ferrara, MD, PhD, the molecular biologist credited with helping decipher how tumors grow and now senior deputy director for basic sciences at the University of California, San Diego Moores Cancer Center, was today named one of 11 recipients of the inaugural Breakthrough Prize in Life Sciences, which comes with a $3 million cash award.

The prize is the collaborative creation of Mark Zuckerberg, founder of Facebook, and his wife, Priscilla Chan; Sergey Brin, co-founder of Google and his wife, Anne Wojcicki, founder of the genetics company 23andMe; and Yuri Milner, a Russian businessman and philanthropist who established a similar prize in fundamental physics last year, when $3 million each was awarded to nine researchers.

The Breakthrough Prize honors life scientists who have ambitiously pushed the boundaries of their disciplines, taken risks and impacted lives and society.

Ferrara, who is also a distinguished professor of pathology in the UC San Diego School of Medicine?s Department of Pathology, was recognized for his work identifying the role of the human VEGF gene in promoting angiogenesis ? the formation of new blood vessels that can feed tumor growth ? and subsequent development of two major monoclonal antibody drugs: Bevacizumab (marketed as Avastin), which is used to treat multiple forms of cancer, including breast, brain and colorectal, and ranibizumab (marketed as Lucentis), which treats wet age-related macular degeneration, a leading cause of blindness in the elderly.

"Napoleone's work has profoundly advanced our basic understanding of how cancer develops and grows," said David Brenner, MD, vice chancellor for Health Sciences and dean of the UC San Diego School of Medicine. "More importantly, he helped create brand new drugs and therapies based upon that research to effectively treat a broad range of cancers and other conditions. He continues with those efforts today, pushing himself and colleagues to find better answers to cancer."???

Ferrara, 56, came to UC San Diego last year after a long career at Genentech, the San Francisco-based biotechnology company where he did much of his ground-breaking work. He said that when Breakthrough Prize Foundation president Arthur D. Levinson, chairman of Apple and a former Genentech chief executive, called to tell him he had won, he was ?very much astonished. I didn?t know the award existed.?

?The thing I am most proud of,? said Ferrara, ?is that we?ve advanced the understanding of basic mechanisms of cancer and we?ve been able to help people, both in fighting cancer and restoring visual acuity. It?s that kind of work that I?m continuing at Moores Cancer Center, where I?ll be able to work closely with clinicians and develop new clinical trials.?

Scott Lippman, MD, director of the UC San Diego Moores Cancer Center, said the Breakthrough Prize justly recognizes Ferrara?s seminal research and how it ?has changed therapy for cancer and eye diseases.?

?His work epitomizes our overall effort at Moores Cancer Center: high-risk, high-gain, high-impact achievement and innovation in taking basic-science discovery to the clinic and transforming cancer care.?

Joining Ferrara among the first winners of the Breakthrough Prize are:

  • Cornelia I. Bargmann, Rockefeller University, who studies the nervous system and human behavior
  • David Botstein, Princeton University, who uses the human genome to map disease biomarkers
  • Lewis C. Cantley, Weill Cornell Medical College, who discovered a family of enzymes related to cell and cancer growth
  • Hans Clevers, Hubrecht Institute in the Netherlands, who has parsed how stem cell processes go awry, resulting in cancer
  • Eric S. Lander, Harvard University and the Massachusetts Institute of Technology (MIT), a leader in the Human Genome Project
  • Titia de Lange, Rockefeller University, who studies the protective tips of chromosomes called telomeres
  • Charles L. Sawyer, Memorial Sloan-Kettering Cancer Center, who has investigated the signals that prompt a cell to become cancerous
  • Bert Vogelstein, Johns Hopkins University, who developed a model for how colon cancer progresses and discovered a protein that suppresses tumor growth
  • Robert A. Weinberg, MIT, who discovered the first human oncogene
  • Shinya Yamanaka, Kyoto University and Gladstone Institutes in San Francisco, for his fundamental research of stem cells

The founders of the Breakthrough Prize intend their awards ? which will consist of five honorees in subsequent years, each receiving $3 million ? to boost public attention and awareness of the major players and advances in the life sciences.

There are few limitations on who can win: Anyone can be nominated online at the Breakthrough Prize in Life Sciences Foundation?s website ( . There are no restrictions on age or the number of people who can share the award. The cash prize comes with no constraints on how it can be spent. And individuals can win multiple times. This year?s 11 recipients will form a committee to select future winners.


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Monday, February 18, 2013

Man charged in killings of 2 women in Missouri

This photo provided by the Kansas City (Mo.) Police Department shows Derek Richardson. Richardson, 27, an unemployed Kansas City-area man was arrested Saturday, Feb. 16, 2013 in the killings of two prostitutes whose bodies were found posed on the side of rural Missouri roads nearly a year apart. (AP Photo/ Kansas City (Mo.) Police Department)

This photo provided by the Kansas City (Mo.) Police Department shows Derek Richardson. Richardson, 27, an unemployed Kansas City-area man was arrested Saturday, Feb. 16, 2013 in the killings of two prostitutes whose bodies were found posed on the side of rural Missouri roads nearly a year apart. (AP Photo/ Kansas City (Mo.) Police Department)

(AP) ? A Kansas City-area man was arrested Saturday in the killings of two prostitutes whose bodies were found posed on the side of rural Missouri roads nearly a year apart.

At a news conference Saturday night, authorities said Derek Richardson, 27, has been charged with two counts of first-degree murder and two counts of abandonment of a corpse. His bail is set at $2 million. It wasn't immediately known whether he has an attorney.

"We absolutely stopped a person who was going to kill again," said Kansas City police Sgt. Doug Niemeier, adding that authorities will search across the United States to ensure there weren't other victims.

"We do know that he had travels elsewhere," Niemeier said, "so we will be contacting those states just to make sure."

Police announced earlier this month that the deaths of Tamara Sparks and Nicoleone Reed were linked and asked the public for help. Police said they believed whoever was responsible for the deaths also was the person who lost a size 11, canvas, Crocs-brand shoe at the site where Sparks' body was found.

Niemeier said a tipster contacted police Thursday night because of the description of the shoe.

"Basically the tip was to say he was the one and the shoe was what really matched it," Niemeier said.

Police began trailing Richardson and arrested him late Saturday morning. Niemeier said Richardson confessed to the "intimate details of the crime" and that he didn't know the victims beforehand.

Sparks, 40, was found dead Oct. 4, 2011, on the far northeast side of Kansas City, and Reed, 24, was found Aug. 21 in rural Kearney, northeast of Kansas City. Both bodies were in spots where they could easily be seen, with their pants pulled down and shirts pulled up.

Both women were last seen on St. John Avenue near Independence Avenue in northeast Kansas City, where they worked as prostitutes, police said.

Earlier this month, police said a third woman, who lived on the same street where Sparks and Reed were last seen, was found dumped in late 2011 along the side of a road in Caldwell County, southeast of Cameron. She survived. But authorities didn't say Saturday if her case was connected.

"We have a tremendous amount of follow-up to do now that we have answered some of our own questions," Niemeier said, adding that it "feels good when you can tell a victim's family that their case has been resolved."

Associated Press


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Acer Iconia W700P-6821 11.6 inch Intel Core i5-3317U 1.7GHz/ 4GB DDR3/ 128GB SSD/ Windows 8 Pro Tablet Computer (Silver)

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Part#: W700P-6821
Package: RETAIL
Manufacturer: Acer
Manufacturer Part#: NT.L0RAA.005;W700P-6821
Shipping Weight: 8.90 lbs.(4.05 kg)

Product Info:


    • Mfr Part Number: NT.L0RAA.005;W700P-6821
    • Processor: Intel Core i5-3317U Processor (1.7GHz Clock Speed, 2.6GHz Max Turbo, 3MB Intel Smart Cache, Dual-Core)
    • Chipset: Intel HM77 Express
    • Memory: 4GB DDR3 SDRAM Memory
    • Display: 11.6" Full HD 16:9 (1920 x 1080) CineCrystal Active Matrix TFT Color LCD Multi-touch Display w/ LED Backlight
    • Graphics Module: Intel HD Graphics 4000 Controller
    • Storage: 128GB SATA2 Solid State Drive
    • Audio: Integrated Sound Card, Built-in Speakers and Microphone
    • Connectivity: IEEE 802.11a/b/g/n Wireless LAN; Bluetooth 4.0 + HS
    • Interface: 1x USB 3.0 Port, 1x Micro HDMI Port, 1x Audio Line Out
    • Card Reader: 1x MicroSD Card Reader
    • Camera: Built-in Front and Rear-facing HD Cameras
    • Battery: 3-cell 4850mAh Li-polymer Battery, Up to 9 Hours of Battery Life
    • AC Adapter: 65W
    • Color: Silver
    • Dimensions (WxDxH): 11.6 x 7.5 x 0.5 inch
    • Operating System: Windows 8 Pro 64-bit
    ** This item is only eligible to be shipped using UPS Ground. **
    ** This item must be shipped to the billing address if paid with Credit/Debit Card.**
    ** This item is eligible for replacement only and is NON REFUNDABLE. **
    ** Product warranty is provided solely by the product manufacturer. **

* Product descriptions and part numbers are subject to change, and may not reflect manufacturer product changes. Please check the manufacturer's website and use the item's manufacturer part number to find the most up to date product description.
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Thursday, February 14, 2013

Sales Manager at Eco-Business |

Based in Singapore, the leading portal for cleantech and sustainable business in Asia Pacific, providing its readers with regional news & opinion, and offering its clients a range of online marketing solutions.

We?re growing fast and looking for a dynamic, target-driven B2B sales professional to join us as Sales Manager and sell our full range of ?off-the-shelf? marketing products and services.

This is a key role with the company, so you must have a history of success in media sales, a passion for online media, and a keen interest in ? and at the very minimum a basic understanding of ? environmental sustainability and how it relates to the business world.

REQUIRED experience:

  • B2B media sales
  • Selling creative marketing solutions & integrated marketing bundles
  • Production of high quality sales proposals
  • Client account management & development
  • Managing business development campaigns
  • Proven ability to consistently hit sales targets

The following experience will be very useful to this job application:

  • Online advertising sales for a B2B portal
  • Use of a CRM system for sales administration
  • Events industry (workshops/conferences)
  • Sales of commissioned editorial
  • Strong social media skills
  • Production of company marketing collaterals
  • Selling and managing research projects
  • Asian languages other than English
  • Managing team members

You must be well organised, have excellent written and spoken English, a relaxed and confident phone manner, solid PC & internet skills, and a sharp eye for detail. On top of this, you must have a positive and engaging personal manner (for face-to-face client meetings), and the drive to succeed in this role.

The right candidate will be rewarded with strong support, recognition, fast progression, a flexible work environment, and an attractive salary package including an industry-beating commission structure.

This role is based in Singapore. Immediate interview and start possible.

To apply please email your CV and a covering letter explaining why you would be best for this role, to

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Monday, February 11, 2013

John Deere Thong Womens G String Lingerie Sexy Plaid Birthday Present Wedding Bridal Bachelorette Party Gift Idea by JustThongs

Great gift idea for bachelorette party, bachelor party, bridal shower and birthday

Also makes a fun surprise gift-
Women surprise your man
Men surprise your woman

Please specify size when
ordering in "note from buyer"

Same as Victoria's Secret

*Gentle wash, no dryer*

Thongz is not affiliated with or sponsored by John Deere.
This item is not a licensed John Deere product, it is however
handmade from licensed John Deere fabric and is intended
for personal use only.

Have any questions? Contact the shop owner.


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